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Best Hotels in South America: Luxury Resorts, Iconic City Hotels & Unforgettable Escapes

Best Hotels in South America – A Comprehensive 2025 Guide

Ultimate Guide to
South America’s Best Hotels


The Andean Region Hotels:
Historic Haciendas and Sacred Valleys

The Andean region of South America, encompassing Peru, Ecuador, and Bolivia, offers a spectacular tapestry of ancient civilizations, colonial cities, and dramatic high-altitude landscapes. The hotel scene here is a captivating blend of restored historic mansions and luxurious lodges that serve as gateways to some of the world’s most iconic sites. The search for the best hotels in Peru often begins in Cusco, the former capital of the Inca Empire. Here, stunning properties like the Belmond Hotel Monasterio, a converted 16th-century monastery, and the Inkaterra La Casona, a colonial manor, offer guests a deep sense of history and place. These hotels provide a perfect base for acclimatizing before heading into the Sacred Valley and to Machu Picchu, where exclusive hideaways like the Sanctuary Lodge offer unparalleled proximity to the ancient citadel.

Ecuador presents its own unique brand of luxury, from the historic heart of Quito to the extraordinary biodiversity of the Galápagos Islands and the Amazon rainforest. In Quito’s old town, a UNESCO World Heritage site, the Casa Gangotena offers opulent accommodation in a restored presidential mansion overlooking Plaza San Francisco. For a truly unique experience, Mashpi Lodge, a cocoon of contemporary luxury set in the middle of a cloud forest, provides a breathtaking immersion in nature with its panoramic glass walls and observation platforms. In the Galápagos, luxury is defined by intimate and exclusive expedition cruises or unique eco-lodges like Pikaia Lodge on Santa Cruz Island, which combine land-based comfort with sustainable practices and wildlife exploration.

Bolivia, a land of surreal landscapes, offers experiences that are more rugged and adventurous, yet increasingly luxurious. From the dazzling white plains of the Salar de Uyuni, unique salt hotels provide an otherworldly stay, offering unparalleled views of the star-filled night sky. In the capital, La Paz, luxury hotels provide comfortable havens in the world’s highest capital city. The best hotels in the Andean region are defined by their profound connection to the history, culture, and nature that surrounds them. Whether you are staying in a colonial masterpiece in Cusco, a cloud forest marvel in Ecuador, or a salt palace in Bolivia, these accommodations are integral parts of an unforgettable South American journey.

Name Location Type Stars
Belmond Hotel Monasterio Cusco, Peru Historic Monastery Hotel ★★★★★
Mashpi Lodge Mashpi, Ecuador Cloud Forest Lodge ★★★★★
Inkaterra La Casona Cusco, Peru Colonial Manor Hotel ★★★★★
Casa Gangotena Quito, Ecuador Historic Luxury Hotel ★★★★★
Belmond Sanctuary Lodge Machu Picchu, Peru Unique Lodge ★★★★★
Tambo del Inka, a Luxury Collection Resort Sacred Valley, Peru Luxury Valley Resort ★★★★★
Pikaia Lodge Galápagos, Ecuador Luxury Eco-Lodge ★★★★★
Palacio del Inka, a Luxury Collection Hotel Cusco, Peru Historic Palace Hotel ★★★★★
Palacio de Sal Salar de Uyuni, Bolivia Salt Hotel ★★★★
Hacienda Zuleta Imbabura, Ecuador Historic Hacienda ★★★★
Inkaterra Machu Picchu Pueblo Hotel Aguas Calientes, Peru Luxury Nature Resort ★★★★★
Aranwa Sacred Valley Hotel & Wellness Sacred Valley, Peru Hacienda Resort ★★★★★
Finch Bay Galapagos Hotel Galápagos, Ecuador Eco-Hotel ★★★★★
Atix Hotel La Paz, Bolivia Design Hotel ★★★★★
Sumaq Machu Picchu Hotel Aguas Calientes, Peru Luxury Hotel ★★★★★
Belmond Miraflores Park Lima, Peru Luxury Hotel ★★★★★
Hotel del Parque Guayaquil, Ecuador Historic Boutique Hotel ★★★★★
Belmond Palacio Nazarenas Cusco, Peru Palace Hotel ★★★★★
Titilaka, a Relais & Châteaux Lake Titicaca, Peru Luxury Lodge ★★★★★
Illa Experience Hotel Quito, Ecuador Boutique Hotel ★★★★
Hotel B Lima, Peru Arts Boutique Hotel ★★★★
Explora Valle Sagrado Sacred Valley, Peru All-Inclusive Lodge ★★★★★
Sacha Lodge Amazon, Ecuador Jungle Lodge ★★★★
CIRQA – Relais & Châteaux Arequipa, Peru Historic Monastery Hotel ★★★★★
Hotel Luna Salada Salar de Uyuni, Bolivia Salt Hotel ★★★★
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Brazil Hotels:
Bossa Nova Chic and Amazonian Adventures

Brazil is a country of continental proportions, with a spirit and energy that is reflected in its diverse and vibrant hotel scene. From the iconic beaches of Rio de Janeiro to the depths of the Amazon rainforest, the best hotels in Brazil offer a captivating blend of natural beauty and sophisticated style. The search for luxury often starts in Rio, where legendary hotels like the Copacabana Palace, A Belmond Hotel, have been symbols of glamour for a century. Overlooking the famous mosaic promenade, this art deco masterpiece is an institution. In the chic neighborhood of Ipanema, the Hotel Fasano Rio de Janeiro, with its Philippe Starck design and rooftop infinity pool offering stunning views of Two Brothers mountain, embodies the city’s cool, bossa nova vibe.

Beyond Rio, Brazil’s vast coastline is home to secluded and stylish beach retreats. In the state of Bahia, resorts like the UXUA Casa Hotel & Spa in Trancoso offer a unique experience, with guests staying in beautifully restored fishermen’s houses centered around a town square. This focus on “barefoot luxury” and authentic local culture is a hallmark of the best Brazilian beach hotels. Further south, near Florianópolis, Ponta dos Ganchos is an exclusive, adults-only resort on a private peninsula, offering unparalleled privacy and romance. These properties are perfect for those seeking to escape and immerse themselves in Brazil’s relaxed coastal lifestyle.

For the truly adventurous, the Brazilian Amazon and Pantanal wetlands offer incredible eco-lodges that provide a comfortable base for exploring some of the most biodiverse regions on Earth. Lodges like Anavilhanas Jungle Lodge in the Amazon and Caiman Ecological Refuge in the Pantanal are leaders in sustainable tourism, combining wildlife excursions led by expert naturalist guides with surprisingly luxurious amenities. In the heart of the country’s economic hub, São Paulo, the Palácio Tangará and Hotel Fasano São Paulo offer opulent urban sanctuaries. From the glamour of the Copacabana to the thrill of a jaguar safari, Brazil’s top hotels deliver unforgettable experiences infused with the country’s infectious energy and warmth.

Name Location Type Stars
Copacabana Palace, A Belmond Hotel Rio de Janeiro Iconic Luxury Hotel ★★★★★
Hotel Fasano Rio de Janeiro Rio de Janeiro Design Hotel ★★★★★
Palácio Tangará – an Oetker Collection Hotel São Paulo Urban Palace Hotel ★★★★★
UXUA Casa Hotel & Spa Trancoso, Bahia Boutique Design Hotel ★★★★★
Ponta dos Ganchos Exclusive Resort Governador Celso Ramos Luxury Resort ★★★★★
Hotel das Cataratas, A Belmond Hotel Iguassu Falls Unique Lodge ★★★★★
Hotel Fasano São Paulo São Paulo Luxury Hotel ★★★★★
Anavilhanas Jungle Lodge Amazon, Novo Airão Jungle Lodge ★★★★
Emiliano Rio Rio de Janeiro Luxury Hotel ★★★★★
Caiman Ecological Refuge Pantanal, Miranda Safari Lodge ★★★★★
Fasano Salvador Salvador, Bahia Historic Luxury Hotel ★★★★★
Txai Resort Itacaré Itacaré, Bahia Luxury Eco Resort ★★★★★
Rosewood São Paulo São Paulo Luxury Art Hotel ★★★★★
Kurotel – Centro Médico de Longevidade Gramado Luxury Wellness Spa ★★★★★
Fairmont Rio de Janeiro Copacabana Rio de Janeiro Luxury Hotel ★★★★★
Campo Bahia Hotel Villas Spa Santo André, Bahia Luxury Villa Resort ★★★★★
JW Marriott Hotel São Paulo São Paulo Luxury Hotel ★★★★★
Cristalino Lodge Alta Floresta, Amazon Eco-Lodge ★★★★
Santa Teresa Hotel RJ – MGallery Rio de Janeiro Boutique Hotel ★★★★★
Pousada Maravilha Fernando de Noronha Luxury Pousada ★★★★★
Hotel Convento do Carmo Salvador, Bahia Historic Convent Hotel ★★★★★
Botanique Hotel & Spa Campos do Jordão Mountain Spa Hotel ★★★★★
Fasano Boa Vista Porto Feliz Countryside Hotel ★★★★★
Hotel Unique São Paulo Design Hotel ★★★★★
Emiliano São Paulo São Paulo Luxury Hotel ★★★★★
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The Southern Cone Hotels:
Patagonian Lodges and Wine Estates

The Southern Cone of South America, encompassing Argentina, Chile, and Uruguay, is a region of epic landscapes, from the wild glaciers of Patagonia to the celebrated vineyards of Mendoza and the sophisticated streets of Buenos Aires. The hotel scene here is defined by stunningly designed lodges that embrace their remote surroundings and elegant urban properties in historic buildings. The search for the best hotels in Patagonia inevitably leads to architecturally ambitious lodges that blend into the dramatic scenery. In Chilean Patagonia, hotels like Tierra Patagonia and Explora Patagonia offer all-inclusive programs with guided excursions into Torres del Paine National Park, allowing guests to return to understated luxury after a day of adventure.

Argentina and Chile are also world-renowned wine regions, and their hospitality offerings reflect this. In Mendoza, Argentina’s premier wine country, luxurious wine lodges like Cavas Wine Lodge and The Vines Resort & Spa offer stays among the vineyards with the Andes as a backdrop. Guests can enjoy wine tasting, gourmet dining, and even the opportunity to blend their own wine. In Chile, the Colchagua Valley is home to beautiful properties like the Viña Vik, a stunning avant-garde retreat and winery that combines cutting-edge design, art, and nature. These hotels offer a complete immersion in South American wine culture.

The region’s capitals are hubs of European-style elegance and sophistication. Buenos Aires is famous for its grand hotels in neighborhoods like Recoleta, where the Alvear Palace Hotel and Palacio Duhau – Park Hyatt are paragons of belle époque luxury. In Santiago, Chile, modern luxury hotels offer stunning views of the city framed by the Andes. Uruguay provides a chic and relaxed counterpoint, with coastal towns like José Ignacio home to bohemian-chic hotels such as Bahia Vik and the celebrated country retreat, Estancia Vik. From the rugged wilderness of Patagonia to the refined elegance of a Buenos Aires palace, the best hotels in the Southern Cone offer a remarkable range of sophisticated and adventurous travel experiences.

Name Location Type Stars
Explora Patagonia Torres del Paine, Chile Luxury Lodge ★★★★★
Alvear Palace Hotel Buenos Aires, Argentina Iconic Palace Hotel ★★★★★
Tierra Patagonia Hotel & Spa Torres del Paine, Chile Luxury Lodge & Spa ★★★★★
Cavas Wine Lodge Mendoza, Argentina Wine Lodge ★★★★★
Vik Chile Millahue, Chile Design & Wine Hotel ★★★★★
Palacio Duhau – Park Hyatt Buenos Aires Buenos Aires, Argentina Palace Hotel ★★★★★
Estancia Vik José Ignacio José Ignacio, Uruguay Luxury Estancia ★★★★★
Explora Atacama San Pedro de Atacama, Chile All-Inclusive Lodge ★★★★★
Llao Llao Resort, Golf & Spa Bariloche, Argentina Historic Mountain Resort ★★★★★
The Ritz-Carlton, Santiago Santiago, Chile Luxury Hotel ★★★★★
The Vines Resort & Spa Mendoza, Argentina Luxury Wine Resort ★★★★★
Tierra Atacama Hotel & Spa San Pedro de Atacama, Chile Desert Lodge & Spa ★★★★★
Faena Hotel Buenos Aires Buenos Aires, Argentina Design Hotel ★★★★★
Bahia Vik José Ignacio José Ignacio, Uruguay Beachfront Design Hotel ★★★★★
W Santiago Santiago, Chile Design Hotel ★★★★★
Awasi Patagonia – Relais & Châteaux Torres del Paine, Chile Private Villa Lodge ★★★★★
Four Seasons Hotel Buenos Aires Buenos Aires, Argentina Luxury Hotel ★★★★★
Nayara Alto Atacama San Pedro de Atacama, Chile Desert Lodge ★★★★★
Fasano Punta del Este Punta del Este, Uruguay Luxury Resort ★★★★★
EOLO – Patagonia’s Spirit El Calafate, Argentina Luxury Lodge ★★★★
The Singular Patagonia Puerto Natales, Chile Historic Hotel ★★★★★
Alvear Art Hotel Buenos Aires, Argentina Modern Luxury Hotel ★★★★★
Mandarin Oriental, Santiago Santiago, Chile Luxury Resort Hotel ★★★★★
Entre Cielos Wine & Spa Hotel Mendoza, Argentina Wine Hotel & Spa ★★★★
Lapostolle Residence Colchagua Valley, Chile Luxury Wine Villa ★★★★★
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Colombia & Venezuela Hotels:
Colonial Cities and Caribbean Coasts

Colombia and Venezuela, located in the northernmost part of the continent, boast a rich history, stunning Caribbean coastlines, and vibrant cultures. Colombia, in particular, has undergone a remarkable transformation and is now one of South America’s most exciting travel destinations, with a rapidly improving luxury hotel scene. The crown jewel of Colombian hospitality is the historic walled city of Cartagena. A search for the best hotels in Cartagena reveals enchanting boutique properties in beautifully restored colonial mansions. Hotels like the Sofitel Legend Santa Clara, a converted 17th-century convent, and the Casa San Agustín, with its elegant rooms and private pools, offer a magical blend of history, romance, and five-star luxury. These hotels provide an intimate and sophisticated base for exploring the city’s colorful streets and vibrant culture.

Beyond Cartagena, Colombia’s diverse landscapes offer a range of unique hotel experiences. In the bustling capital, Bogotá, modern luxury hotels like the Four Seasons Hotel Casa Medina and the W Bogotá cater to a discerning international clientele with sophisticated design and world-class service. The country’s coffee region, a UNESCO World Heritage landscape, is home to charming haciendas and eco-lodges that allow guests to immerse themselves in the coffee-making process while enjoying the beautiful scenery. In the remote Tayrona National Park area, eco-habs and luxury lodges offer stays that are deeply connected to nature, with stunning views of where the jungle meets the Caribbean Sea.

While Venezuela’s tourism industry has faced significant challenges, the country possesses incredible natural wonders, including Angel Falls and the pristine archipelago of Los Roques. In the past, luxury “posadas” (inns) in Los Roques offered a chic, Robinson Crusoe-style escape. As the situation evolves, the potential for luxury travel remains immense. For now, Colombia is leading the way in this region, with a hotel sector that is booming with confidence and quality. From the colonial splendor of Cartagena to the modern elegance of Bogotá, the best hotels in this part of South America offer a warm welcome and a gateway to a region brimming with life, color, and resilience.

Name Location Type Stars
Sofitel Legend Santa Clara Cartagena Cartagena, Colombia Historic Convent Hotel ★★★★★
Casa San Agustín Cartagena, Colombia Luxury Boutique Hotel ★★★★★
Four Seasons Hotel Casa Medina Bogotá Bogotá, Colombia Historic Luxury Hotel ★★★★★
W Bogotá Bogotá, Colombia Design Hotel ★★★★★
Hacienda Bambusa Coffee Region, Colombia Hacienda Hotel ★★★★
Nacar Hotel Cartagena, Curio Collection Cartagena, Colombia Boutique Hotel ★★★★★
The Charlee Hotel Medellín, Colombia Lifestyle Hotel ★★★★★
Hotel Charleston Santa Teresa Cartagena Cartagena, Colombia Historic Hotel ★★★★★
JW Marriott Hotel Bogota Bogotá, Colombia Luxury Hotel ★★★★★
Eurobuilding Hotel & Suites Caracas Caracas, Venezuela Business Hotel ★★★★★
Hotel Las Islas Barú, Colombia Bungalow Resort ★★★★★
Medellín Marriott Hotel Medellín, Colombia Luxury Hotel ★★★★★
Sofitel Bogota Victoria Regia Bogotá, Colombia Luxury Hotel ★★★★★
Amara Isabella Cartagena, Colombia Boutique Hotel ★★★★★
Sazagua Hotel Boutique Pereira, Colombia Boutique Hotel ★★★★
Bio Habitat Hotel Armenia, Colombia Eco-Lodge ★★★★
Hyatt Regency Cartagena Cartagena, Colombia Luxury Hotel ★★★★★
The Click Clack Hotel Medellín Medellín, Colombia Design Hotel ★★★★
Grand Hyatt Bogota Bogotá, Colombia Luxury Hotel ★★★★★
Hotel Quadrifolio Cartagena, Colombia Boutique Hotel ★★★★
Hotel Cayena-Caracas Caracas, Venezuela Luxury Hotel ★★★★★
InterContinental Medellin Medellín, Colombia Resort Hotel ★★★★★
Hotel Boutique Don Pepe Santa Marta, Colombia Boutique Hotel ★★★★
Four Seasons Hotel Bogota Bogotá, Colombia Luxury Hotel ★★★★★
Bastión Luxury Hotel Cartagena, Colombia Luxury Hotel ★★★★★
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The Guianas & Lesser-Known Gems Hotels:
Eco-Lodges and Raw Nature

The northeastern corner of South America, comprised of Guyana, Suriname, and French Guiana, is a region of untamed wilderness, rich cultural heritage, and emerging tourism. This is one of the planet’s last frontiers for nature lovers, and the hospitality scene reflects this, with a focus on authentic, eco-conscious lodges that provide access to incredible biodiversity. The search for the best hotels in Guyana will almost certainly lead you away from the capital, Georgetown, and deep into the interior. Here, lodges like Cara Lodge in Georgetown offer historic colonial charm, but the true gems are remote eco-lodges that serve as bases for exploring the vast rainforest. These lodges offer experiences like jaguar tracking, bird watching, and visiting mighty waterfalls like Kaieteur Falls.

Suriname, with its unique Dutch colonial architecture and vibrant mix of cultures, offers a different experience. In the capital, Paramaribo, a UNESCO World Heritage site, hotels are often housed in beautifully restored wooden buildings. The Torarica Resort offers a comfortable, resort-style base for exploring the city and its surroundings. Deeper in the Surinamese jungle, lodges provide immersive experiences in pristine nature, often run by or in partnership with local indigenous communities. These stays offer a chance to disconnect from the modern world and connect with a raw, powerful environment and the diverse cultures that call it home.

French Guiana, an overseas department of France, provides a unique blend of European standards and Amazonian wilderness. The primary visitor attraction is the Guiana Space Centre, but for nature lovers, lodges provide access to primary rainforests and diverse wildlife. While the luxury hotel infrastructure in the Guianas is not as developed as in other parts of the continent, the richness of the experience is unparalleled for adventurous travelers. The best accommodations in this region are not defined by traditional five-star metrics but by their exclusivity, their connection to pristine nature, and their ability to offer a truly authentic and unforgettable journey into one of the world’s last great wildernesses.

Name Location Type Stars
Guyana Marriott Hotel Georgetown Georgetown, Guyana Business Hotel ★★★★★
Courtyard by Marriott Paramaribo Paramaribo, Suriname Business Hotel ★★★★
Mercure Cayenne Royal Amazonia Cayenne, French Guiana Resort Hotel ★★★★
Cara Lodge Georgetown, Guyana Historic Hotel ★★★
Torarica Resort Paramaribo, Suriname Resort & Casino ★★★★
Hub Hotel Asuncion Asunción, Paraguay Business Hotel ★★★★
Pegasus Hotel Guyana Georgetown, Guyana Business Hotel ★★★★
Krasnapolsky Hotel Paramaribo Paramaribo, Suriname City Hotel ★★★★
Grand Hotel Montabo Cayenne, French Guiana Seaside Hotel ★★★★
Esplendor by Wyndham Asuncion Asunción, Paraguay Design Hotel ★★★★
Rewa Eco-Lodge Rupununi, Guyana Eco-Lodge ★★★
Jacana Amazon Wellness Resort Commewijne, Suriname Wellness Resort ★★★★
Bourbon Conmebol Asuncion Convention Hotel Asunción, Paraguay Convention Hotel ★★★★★
Atta Rainforest Lodge & Iwokrama Canopy Iwokrama Forest, Guyana Rainforest Lodge ★★★
Lodge des Chutes de Carbet Capesterre, French Guiana Nature Lodge ★★★
Eco Resort-Inn Paramaribo, Suriname Eco-Resort ★★★
Sheraton Asuncion Hotel Asunción, Paraguay Business Hotel ★★★★★
Rock View Lodge Rupununi, Guyana Ranch & Lodge ★★★
Royal Torarica Paramaribo, Suriname Luxury Hotel ★★★★
La Mision Hotel Boutique Asunción, Paraguay Boutique Hotel ★★★★
Hotel des Roches Kourou, French Guiana Beach Hotel ★★★
Grand Coastal Hotel Georgetown, Guyana Boutique Hotel ★★★
Ramada by Wyndham Princess Paramaribo Paramaribo, Suriname Hotel & Casino ★★★★
Dazzler by Wyndham Asuncion Asunción, Paraguay Business Hotel ★★★★
Karanambu Lodge Rupununi, Guyana Conservation Lodge ★★★
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